Which of the following terms is defined as "the international use of the Government-issued charge card in violation of applicable regulations"?

The term that best defines "the international use of the Government-issued charge card in violation of applicable regulations" is abuse. In the context of the Governmentwide Commercial Purchase Card (GPC) program, abuse refers to the improper use of the card that constitutes a deviation from the established guidelines or regulations. This includes cases where the purchase card is used in a manner that is not authorized, such as making international transactions without proper approval, which is against the policy.

Abuse is significant because it indicates a misuse of the government resources and can lead to serious consequences, including accountability measures for the individual involved. In this context, it highlights the importance of adherence to regulations intended to manage government spending and ensure appropriate usage of government-issued charge cards.

Other terms like misuse, fraud, and negligence may carry different implications. Misuse generally suggests improper use but may not specify a violation of regulations, while fraud includes the intent to deceive, which is not inherent in the definition provided. Negligence refers to a failure to take proper care, which may not necessarily imply intentional wrongdoing. Therefore, abuse correctly encompasses the international use of the card in a way that directly contravenes established rules.